The treatment of alcohol dependence

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[The pharmacologic treatment of the alcohol dependence].

The pharmacological intervention can play a crucial role in the reduction of craving and drinking and the maintenance of abstinence. This article reviews pharmacotherapy for alcohol dependence with an emphasis on the naltrexone, dissulfiram and acamprosate. The opioid antagonist naltrexone lowers relapse rate, reduces drinking days and prolongs periods of abstinence. Acamprosate restores the no...

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The treatment of alcohol dependence--new horizons.

264 The fact that alcohol is an addictive drug has been known to man for millennia. Alcohol abuse/dependence is the most common substance-related disorder. A drug can be defined as a substance that produces tolerance (increasingly large amounts are needed to produce the same effect) and withdrawal (psychological and physical distress develop after substance use ceases). The addicted person suff...

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Alcohol Dependence--neurobiology and Treatment.

The consequences of alcohol dependence concern serious health care, social and economic problems. The scope of many studies is to better understand mechanisms underlying alcohol addiction in order to work out new, more effective treatment strategies. Alcohol affects many neurotransmission systems within the brain. In general, acute alcohol enhances inhibitory transmission, up-regulating the GAB...

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ژورنال

عنوان ژورنال: Current Opinion in Psychiatry

سال: 2007

ISSN: 0951-7367

DOI: 10.1097/yco.0b013e3280fa837d